APIs/INTERMEDIATES

Amoxicillin-Clavulanate Potassium

Amoxicillin-clavulanate potassium" is a drug combination used to treat bacterial infections. It involves adding the chemical clavulanate potassium to the antibiotic amoxicillin, which enhances the antibiotic's effectiveness by increasing the amount of time it remains active in the body. This combination is commonly prescribed to treat various bacterial infections in different parts of the body, such as the ears, lungs, sinuses, skin, and urinary tract. Amoxicillin is a penicillin antibiotic that fights bacteria, while clavulanate potassium is a beta-lactamase inhibitor that helps prevent certain bacteria from becoming resistant to the antibiotic.

Ampicillin Trihydrate

Ampicillin Trihydrate is a form of ampicillin, which is a semisynthetic penicillin antibiotic derived from the basic penicillin nucleus, 6-aminopenicillanic acid. Ampicillin trihydrate is slightly soluble in water, while ampicillin sodium, another form of ampicillin, is very soluble in water, 0.9% sodium chloride, and in dextrose solutions. Ampicillin is used to treat various bacterial infections such as meningitis, infections of the throat, sinuses, lungs, reproductive organs, urinary tract, and gastrointestinal tract.

Amoxicillin Trihydrate

Amoxicillin trihydrate is a common form of amoxicillin, an antibiotic used to treat bacterial infections. It is a hydrate form of amoxicillin, where three molecules of water are associated with each molecule of amoxicillin. This form is often used in the production of injectable medicinal products.

Azithromycin

Azithromycin is a macrolide antibiotic used in the pharmaceutical industry. It is derived from erythromycin and is classified as an azalide, which is a subclass of macrolide antibiotics. This antibiotic is commonly sold under the brand names Zithromax and Azasite and is utilized for treating various bacterial infections such as middle ear infections, strep throat, pneumonia, traveler's diarrhea, and certain intestinal infections. Azithromycin is available in different forms including film-coated tablets, capsules, oral suspensions, intravenous injections, granules for suspension, and ophthalmic solutions.

Ampicillin Tri Hydrate Compacted

Ampicillin Trihydrate compacted in pharmaceuticals is a semi-synthetic broad-spectrum penicillin used to treat various bacterial infections. It is available in white, practically odorless crystalline powder form and is indicated for inflammations and microbial infections of the ear, such as otitis external, eczema, mycosis, and furunculosis of the meatus. The chemical formula for Ampicillin Trihydrate is C16H19N3O4S, 3H2O, and it complies with pharmacopoeial quality standards like USP, BP, and EP. This antibiotic is commonly used in both human and veterinary medicine for its effectiveness against a wide range of bacteria.

Ampicillin Trihydrate Powder

Ampicillin Trihydrate Powder in the pharmaceutical industry is a white crystalline powder that is commonly used to treat various bacterial infections. It belongs to the penicillin class of antibiotics and works by inhibiting the growth of bacteria. Ampicillin Trihydrate is described as practically insoluble in alcohol, ether, and fatty oils, but slightly soluble in water. It is a key medication for combating respiratory tract infections, urinary tract infections, meningitis, salmonellosis, and endocarditis, among others.

Cefixime

Cefixime is a third-generation cephalosporin antibiotic used to treat susceptible Gram-negative and Gram-positive bacterial infections. It is sold under the brand name Suprax and others, and is used to treat a variety of bacterial infections, including otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease. Cefixime works by disrupting the bacteria's cell wall, leading to its death. It is available as a generic medication in the United States and is on the World Health Organization's List of Essential Medicines.

Ceftriaxone Sodium

Ceftriaxone sodium is an antibiotic used to treat bacterial infections. It belongs to a group of medications called cephalosporin antibiotics and is administered via injection by healthcare providers in hospitals or clinics. Ceftriaxone sodium is available under brand names like Ceftrisol Plus® and Rocephin® and should not be used to treat viral infections like colds or the flu. It is essential to follow the prescribed dosage and administration instructions carefully, and if administered at home, patients should be trained on how to prepare and administer the medication. Ceftriaxone sodium may interact with other medications, so it is crucial to inform healthcare providers about all medicines, herbs, or supplements being taken. Additionally, caution is advised when using ceftriaxone sodium with certain substances like calcium-containing solutions to avoid potential adverse effects.

Cefoperazone

Cefoperazone is a bactericidal antibiotic that inhibits bacterial cell wall synthesis. It is a third-generation cephalosporin semi-synthetic antibiotic effective against a broad spectrum of gram-negative bacteria, including those resistant to other beta-lactam antibiotics. Cefoperazone is often used in combination with Sulbactam, a beta-lactamase inhibitor, to enhance the activity of penicillin against various bacteria. This antibiotic is indicated for treating infections in the respiratory tract, urinary tract, abdominal area, blood, skin, soft tissues, bones, joints, and more.

Cloxacillin Sodium

Cloxacillin sodium sterile refers to a form of the antibiotic cloxacillin that is prepared in a sterile manner to ensure its safety and efficacy for medical use. This sterile form of cloxacillin sodium is commonly used for the treatment of various bacterial infections, including those caused by beta-hemolytic streptococci, pneumococci, and staphylococci. The sterile preparation of cloxacillin sodium is crucial to prevent contamination and ensure that the medication remains effective when administered to patients.

Levofloxacin

Levofloxacin is a broad-spectrum antibiotic belonging to the fluoroquinolone drug class. It is the left-handed isomer of the medication ofloxacin, used to treat various bacterial infections such as respiratory tract infections, urinary tract infections, pneumonia, prostatitis, anthrax, and more. Levofloxacin is available in different forms like tablets, intravenous solutions, and eye drops. It is essential to note that Levofloxacin should be used as prescribed by a healthcare professional, and it is crucial to complete the full course of treatment even if symptoms improve. Levofloxacin is a critical medication listed on the World Health Organization's List of Essential Medicines and is commonly prescribed in the United States.

Meropenem

Meropenem is a broad-spectrum antibacterial agent of the carbapenem family, indicated as empirical therapy prior to the identification of the causative organisms in a variety of bacterial infections. It is effective against a wide range of Gram-positive and Gram-negative bacteria, including anaerobes, and has a similar spectrum to imipenem, although it is more active against Enterobacteriaceae and less active against Gram-positive bacteria. Meropenem is frequently used in the treatment of febrile neutropenia, a condition that frequently occurs in patients with hematological malignancies and cancer patients receiving anticancer drugs. It is approved for complicated skin and skin structure infections, complicated intra-abdominal infections, and bacterial meningitis.

Metformin HCL

Metformin HCL, also known as metformin hydrochloride, is a medication used for the treatment of type 2 diabetes. It is a biguanide anti-hyperglycemic agent that works by decreasing glucose production in the liver, increasing the insulin sensitivity of body tissues, and reducing the amount of glucose made in the liver. It is often used in combination with a diet and exercise program and may be used as monotherapy or with other antidiabetic medications.

Ofloxacin

Ofloxacin is a synthetic fluoroquinolone antibacterial agent used in the treatment of bacterial infections in various parts of the body, including the respiratory tract, kidney, skin, and others. It works by inhibiting the supercoiling activity of bacterial DNA gyrase, which halts DNA replication. Ofloxacin is available in multiple strengths as a tablet, an oral suspension, and an injectable solution, as well as in the form of eye drops and ear drops. It is also available in combination with ornidazole. Resistance to ofloxacin and other fluoroquinolones may evolve rapidly, even during a course of treatment, and numerous pathogens now exhibit resistance worldwide.

Paracetamol

Paracetamol, also known as acetaminophen, is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely used over-the-counter medication, with common brand names including Tylenol and Panadol. Paracetamol is synthesized by acetylation of 4-aminophenol using acetic acid or acetic anhydride. It exhibits antipyretic and moderate anti-inflammatory effects.

Pantoprazole Sodium

Pantoprazole sodium is a proton pump inhibitor used to treat certain stomach and esophagus problems like acid reflux by reducing the amount of acid produced in the stomach. It is available in different dosage forms and is prescribed for conditions such as erosive esophagitis, heartburn, and excess stomach acid production, like in Zollinger-Ellison syndrome. Pantoprazole sodium should be taken as directed by a healthcare professional and may interact with other medications, affecting their efficacy. It is important to follow storage instructions, take the medication with food, and not crush or chew the tablets.

Pantoprazole Sodium Sesquihydrate

Pantoprazole Sodium Sesquihydrate is a compound used in medications like Protonix, which is a proton pump inhibitor (PPI) that inhibits gastric acid secretion. It is a white to off-white crystalline powder with weakly basic and acidic properties, and it is freely soluble in water. The empirical formula for pantoprazole sodium sesquihydrate is C16H14F2N3NaO4S · 1.5H2O, with a molecular weight of 432.37. This compound is commonly used in the treatment of conditions like reflux oesophagitis or reflux disease, with dosages varying based on factors like age and weight.

Piperacillin And Tazobactam

Piperacillin and tazobactam are a combination penicillin antibiotic used to treat various bacterial infections caused by susceptible organisms. Piperacillin is the penicillin component, while tazobactam is a beta-lactamase inhibitor that helps extend piperacillin's spectrum of activity by protecting it from bacterial enzymes that can degrade it. This combination is effective against a wide range of infections, including intra-abdominal, skin/soft tissue, and respiratory tract infections.

Pantoprazole Sodium Sterile

Pantoprazole Sodium Sterile in pharmaceuticals refers to a sterile form of pantoprazole sodium, a proton pump inhibitor (PPI) used to reduce gastric acid secretion. This sterile version is intended for intravenous administration and comes in a freeze-dried, white to off-white powder form. It is reconstituted with a specific volume of Sodium Chloride Injection to achieve a certain concentration for intravenous infusion. The stability of the solution is pH-dependent, and it should be visually inspected for particulate matter and discoloration before administration. The reconstituted solution has a limited storage time at room temperature and should not be frozen. Pantoprazole Sodium Sterile is crucial for patients who require rapid acid reduction and cannot take oral medications.

Pantoprazole Sesquithydrate

Pantoprazole Sesquithydrate is a white to off-white crystalline powder and is the sodium salt of pantoprazole, a proton pump inhibitor (PPI) used in the pharmaceutical industry. PPIs are a class of drugs that decrease the amount of acid produced in the stomach, and pantoprazole is specifically used to treat certain stomach and esophagus problems such as acid reflux disease. It works by blocking the action of an enzyme in the stomach called the proton pump, which is responsible for producing acid. Pantoprazole is available in both delayed-release tablets and granules for oral suspension, and it is usually taken once daily with or without food, depending on the formulation.

Sulbactam Sodium

Sulbactam sodium is a beta-lactamase inhibitor that is used in combination with beta-lactam antibiotics to inhibit beta-lactamase, an enzyme produced by bacteria that can destroy the antibiotics. It is a derivative of the basic penicillin nucleus and acts as a suicide inhibitor of beta-lactamase, protecting more potent beta-lactam antibiotics like ampicillin. Sulbactam sodium is primarily used to enhance the effectiveness of antibiotics by preventing the breakdown of the antibiotics by bacterial enzymes.

Sorbitol

Sorbitol in pharmaceuticals is a sugar alcohol commonly used as an excipient in various drug formulations. It is chemically inert, stable under specific conditions, and resistant to fermentation by many microorganisms. Sorbitol is utilized as a diluent in tablets, a plasticizer in capsules, a vehicle in liquid preparations, and for protein stabilization in biologic formulations. Additionally, it serves as an osmotic laxative and can be used analytically to assess liver blood flow. Sorbitol is produced by hydrogenation of glucose and is available in different forms like crystalline powder, granules, flakes, or pellets, offering various functionalities such as humectant, sweetening agent, and stabilizer in pharmaceutical products.